Case Report
Mammary granuloma revealing multisystemic sarcoidosis
- By Abir derbel, Wiem Feki, Dora Zghal, Mouna Guermazi, Zaineb Mnif, Mouna Snoussi, Sameh Marzouk - 06 Oct 2025
- Journal of Applied Health Sciences and Medicine, Volume: 5, Issue: 10, Pages: 17 - 20
- https://doi.org/10.58614/jahsm5103
- Received: 01.09.2025; Accepted: 25.09.2025; Published: 06.10.2025
Abstract
Sarcoidosis is an inflammatory granulomatous disease that can affect any organ system. Axial bone involvement and osteolytic lesion of the spine and pelvic bone was exceptionally reported. That shouldn’t be easily diagnosed as osseous sarcoidosis. Also, mammary granuloma was rarely reported as a manifestation of systemic sarcoidosis. Herein, we report a case of a 56-year-old woman who presented with swelling in her right breast. Breast ultrasound showed a nodule of the right breast which histological findings were consistent with granulomatous adenitis. She had also osteolytic bone lesions in the spine without pathological fixation on scintigraphy. Diagnosis of sarcoidosis with uncommon localization: mammary and bone involvement was retained. Such findings in the same patient create a challenge in etiologic diagnosis. Histological confirmation associated to appropriate clinical and radiological presentation are the key of diagnosis.