Article

Studies on the network biology impact in pharmacology and toxicology

Abstract

Network biology is a concept to deals with the biological process on a broader level. The molecular interactions at the cellular level are considered as a network. The aims of network biology are to investigate the components of cellular networks and their interactions. These approaches are widely used in pharmacology and toxicology. The current reports explore the area of application of network biology to understand drug action and drug development studies. Quantitative systems pharmacology (QSP) is a very useful approach to understanding the drug action at the individual level. Systems Recent advances of technology enable toxicology for the understanding toxin effect in the molecular network. Several genetics and epigenetic approaches are used to understand the biological network. Systems pharmacology or system toxicology approaches have enormous prospects for target-based drug design and understanding the adverse side effect or drug resistance in different pathological conditions.

Keywords: Network, System biology, Database, Pharmacology, Toxicology