Counteract Inflammatory Properties of the Purified Ethanolic Extract of Acrostichum aureum (Linn.) Leaf
- By Ajayi Adetola Abiola, O Adedoyin Adetutu - 18 Jan 2022
- Journal of Applied Health Sciences and Medicine, Volume: 1, Issue: 2, Pages: 43 - 47
- Received: 22 November 2021 Accepted: 4 January 2022; Published: 18 January 2022
Inflammation plays a crucial role in the improvement of chronic diseases such as cancer, heart failure, pulmonary embolism, diabetes, arthritis, and headache, stroke all of which provide significant treatment challenges. The counteracting inflammatory impact of cleaned ethanolic crude selection of Acrostichum aureum leaf was investigated. The extract demonstrated considerable counteract inflammatory efficacy in the carrageenan-induced oedema impact in rats, with a decrease in paw volume of 65.90 % (P0.01), equivalent to that generated by the standard drug indomethacin (66.66 %) after 24 hours at a dose of 400 mg/kg body mass. The findings point to purified ethanolic crude extract of Acrostichum aurum's leaf having counteract inflammatory properties, justifying its use in folklore medicines.
Key words: Carrageenan-induced oedema, Acrostichum aureum, Indomethacin Anti-inflammatory, Methanolic extract.